Dimethyl sulfoxide (DMSO) CAS No.: 67-68-5

Dimethyl sulfoxide (abbreviated DMSO) is a sulfur-containing organic compound; molecule formula: (CH3) 2SO; It exhibits as colorless, odorless, hygroscopic and flammable transparent liquid at room temperature. It has both high polarity as well as high-boiling point. It also has aprotic and water-miscible characteristics. It has low toxicity, good thermal stability, and is not miscible with paraffin. It is soluble in water, ethanol, propanol, ether, benzene and chloroform and many other kinds of organic substance and is called as the "universal solvent." It is a common organic solvent which has the strongest dissolving ability. It can dissolve most the organic compounds including carbohydrates, polymers, peptides, as well as many inorganic salts and gases. It can dissolve certain amount solute whose weight is equals to 50-60 percent of itself (other common solvents usually only dissolve 10-20 percent ), so it is very important in the sample management as well as high-speed screening of drugs. Under certain conditions, contact between dimethyl sulfoxide and chloride can even lead to explosive reaction.
Dimethyl sulfoxide is widely used as solvents and reagents, particularly as the processing reagent and spinning solvent at the reaction of acrylonitrile polymerization used for polyurethane synthesis and the spinning solvent. It can also be used as the synthetic solvent for polyamide, polyimide and polysulfone resin as well as the extraction solvents for aromatic hydrocarbon and butadiene extraction solvents and solvents for synthesizing chlorofluoroaniline. In addition, dimethyl sulfoxide can also be directly used as the raw material or carrier of some drug in the pharmaceutical industry. dimethyl sulfoxide itself has various effects such as anti-inflammatory, analgesic, diuretic, and sedative, and thus also being known as "panacea" which is usually as the active ingredient of analgesic medication being added to the drug. It also has special properties of easy penetration through the skin, resulting in personnel feeling of oyster-like flavor. The dimethyl sulfoxide solution of sodium cyanide can cause cyanide poisoning through skin contact while dimethyl sulfoxide itself has a relative low toxicity. dimethyl sulfoxide is widely applied as the extraction agent in a lot of chemical and pharmaceutical companies. However, because of its higher boiling point, it causes very high operating temperatures and further causes the coking of materials, thus affecting the recycling of dimethyl sulfoxide and further cleaning of the equipments as well as resulting in increased energy consumption. Therefore, the recycling of dimethyl sulfoxide has become a bottleneck as its further wide application as extraction agent.

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